Radium ra-223
Radium ra-223 is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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HCPCS
Code | Description |
|---|---|
| A9606 | Radium ra-223 dichloride, therapeutic, per microcurie |
Clinical
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Drug
General
| Drug common name | Radium ra-223 |
| INN | — |
| Description | Radium-223 (223Ra, Ra-223) is an isotope of radium with an 11.4-day half-life. It was discovered in 1905 by T. Godlewski, a Polish chemist from Kraków, and was historically known as actinium X (AcX). Radium-223 dichloride is an alpha particle-emitting radiotherapy drug that mimics calcium and forms complexes with hydroxyapatite at areas of increased bone turnover. The principal use of radium-223, as a radiopharmaceutical to treat metastatic cancers in bone, takes advantage of its chemical similarity to calcium, and the short range of the alpha radiation it emits.
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| Classification | Small molecule |
| Drug class | quaternary ammonium derivatives |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | [223Ra] |
Identifiers
| PDB | — |
| CAS-ID | 15623-45-7 |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297420 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | — |
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